The Physical and Life Sciences Directorate (PLS) supports the Laboratory's science, technological, and programmatic missions in life sciences. The directorate contributes to the rapidly expanding science of biology in areas relevant to important challenges in national security, environmental sustainability, and human health. Integrating bioscience and biotechnology, we perform research in the areas of genome biology, computational biology, molecular toxicology, host-pathogen biology, biochemical structures, assays, genetics and microbial systems, and the intersection of these areas with advances in nanotechnology, and imaging and measurement science.
We work in partnership with LLNL's Global Security Directorate to develop instrumentation to detect biothreat agents at low concentrations in the environment, rapid assays for the detection of disease, and new approaches in bioforensics.
The Biosciences and Biotechnology Division oversees the directorate's life sciences work.
Biosecurity Sensing and Analysis
- Decoding the Origin of a Bioagent
- Single-Particle Aerosol Mass Spectrometry (SPAMS)
- Identifying Airborne Pathogens in Time to Respond
- Host-Pathogen Biology
- Bionanoscience at LLNL
- Mimicking Nature's Crystalline Structures
- Lipid Rafts Observed in Cell Membranes
- Advancing the Frontiers in Cancer Research
- Finding Genes by Leaps and Bounds
- Mining Genomes
- Probing the Secrets of 'Junk' DNA
- Shaping the Future of Aneurysm Treatments
- Developing New Drugs and Personalized Medical Treatment
- Exploring the Link between Diet and Cancer
- Piecing Together the Cyanobacteria Puzzle
- Solving a Nitrogen Fixation Conundrum with NanoSIMS
- Microbial Systems
- Unique Microbial Communities in Acid Mine Drainage
- The Effects of Oxygen on Biochemical Networks and the Evolution of Complex Life
- Host-Pathogen Biology
Science at the Intersection of Physics, Chemistry, Materials, Atmospheric, Earth, and Life Sciences
PLS also conducts a broad range of science at the intersection of multiple disciplines. PLS conducts work in the areas of sensing and analysis; theory, modeling, and computation; ultrafast science; host-pathogen biology; bioanalysis; and assay development and implementation.
One of Lawrence Livermore's emerging missions is to provide the nation with scientific capabilities for defense against biological threats and natural disease outbreaks. Our scientists continue to apply their expertise in materials and analytical methods to develop platforms for chemical and bioagent detection.
2011 Lawrence Livermore National Laboratory and
UC Davis Cancer Center Retreat
Since 2000, Lawrence Livermore National Laboratory (LLNL) and the UC Davis Cancer Center (UCDCC) have collaborated on cancer-related projects of common interest. As a means to continue interactions and to facilitate new partnerships, LLNL and the UCDCC held a one-day retreat at Wente Vineyards on Monday, October 17th, 2011.